Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22767784 | 1.00 | EPHX2 (0.44) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL24849941 | 1.00 | EPHX2 (0.44) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL31245911 | 0.96 | THRA (0.45) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL25230855 | 0.96 | EPHX2 (0.42) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL31245887 | 0.95 | EPHX2 (0.41) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL31245889 | 0.95 | TLR2 (0.43) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL25279941 | 0.95 | EPHX2 (0.41) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL31245892 | 0.95 | LMNA (0.44) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL31245929 | 0.94 | PRKCA (0.50) | EPHX2MAPTMAPK1THRATHRB | |
| SCHEMBL31245896 | 0.94 | EPHX2 (0.41) | EPHX2MAPTMAPK1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274265-A1 | BENZAMIDE COMPOUND AND USE THEREOF | 江苏恒瑞医药股份有限公司 | 2023-01-05 | — | — | WO | disclosed |