Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30159448 | 1.00 | PTGS1 (0.49) | PTGS1PTGS2ALDH1A1MAPK1GRK2 | |
| SCHEMBL10059372 | 0.78 | ALDH1A1 (0.50) | PTGS1PTGS2ALDH1A1KMT2ATSHR | |
| SCHEMBL24850242 | 0.75 | CYP11B2 (0.42) | ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL619634 | 0.75 | MAPK1 (0.78) | ALDH1A1MAPK1TSHRSTAT3PKM | |
| SCHEMBL24850286 | 0.74 | STING1 (0.39) | ALDH1A1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL24849950 | 0.74 | ALDH1A1 (0.37) | ALDH1A1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL22923915 | 0.73 | PTGS1 (0.44) | PTGS1PTGS2ALDH1A1MAPK1GRK2 | |
| SCHEMBL182346 | 0.72 | STIM1 (0.51) | PTGS1PTGS2ALDH1A1MAPK1GRK2 | |
| SCHEMBL146048 | 0.72 | KDM4E (0.56) | ALDH1A1MAPK1TSHRHPGDNPSR1 | |
| Formaldehyde SCHEMBL27289523 | 0.72 | MAPK1 (0.72) | ALDH1A1MAPK1TSHRSTAT3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | ABL2, ABL1, ALK | PTGS1 1671/4885PTGS2 2316/4885ALDH1A1 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.