Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20442882 | 0.82 | MAPT (0.54) | MAPTL3MBTL1MEN1KMT2ATRPM8 | |
| SCHEMBL6129757 | 0.81 | ATM (0.54) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| SCHEMBL7365655 | 0.81 | ATM (0.54) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| SCHEMBL19975277 | 0.81 | ATM (0.54) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| SCHEMBL10062613 | 0.80 | CTSK (0.58) | TRPM8ATMPSMB1 | |
| Hydrochloric Acid SCHEMBL28565967 | 0.79 | ATM (0.52) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| Hydrochloric Acid SCHEMBL28565964 | 0.79 | ATM (0.52) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| SCHEMBL31003034 | 0.78 | PSMB5 (0.48) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| SCHEMBL20012289 | 0.77 | ATM (0.50) | MAPTL3MBTL1MEN1KMT2APSMB5 | |
| SCHEMBL914510 | 0.77 | MAPT (0.67) | MAPTL3MBTL1MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8624051-B2 | Process for the preparation of isoserine derivatives | INDENA S.P.A. (IT) | 2014-01-07 | — | — | US | disclosed |
| US-20130090493-A1 | PROCESS FOR THE PREPARATION OF ISOSERINE DERIVATIVES | INDENA S.P.A (IT) | 2013-04-11 | — | — | US | disclosed |
| EP-2558439-A1 | A PROCESS FOR THE PREPARATION OF ISOSERINE DERIVATIVES | Indena S.p.A. (IT) | 2013-02-20 | — | — | EP | disclosed |
| EP-2380871-B1 | A process for the preparation of isoserine derivatives | INDENA SPA (IT) | 2013-01-09 | — | — | EP | disclosed |
| EP-2380871-A1 | A process for the preparation of isoserine derivatives | Indena S.p.A. (IT) | 2011-10-26 | — | — | EP | disclosed |
| WO-2011128353-A1 | A PROCESS FOR THE PREPARATION OF ISOSERINE DERIVATIVES | INDENA S.P.A. (IT) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090493-A1 | PROCESS FOR THE PREPARATION OF ISOSERINE DERIVATIVES | ICMT, PGLS, PCMT1 | MAPT 3377/4885L3MBTL1 4457/4885MEN1 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.