⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570965 | 0.90 | CA1 (0.41) | — | |
| SCHEMBL10948473 | 0.82 | CA1 (0.45) | — | |
| SCHEMBL6712521 | 0.78 | HDAC4 (0.42) | — | |
| SCHEMBL9673377 | 0.77 | IRAK4 (0.42) | — | |
| SCHEMBL1301200 | 0.77 | ALDH1A1 (0.44) | — | |
| SCHEMBL2885322 | 0.76 | CA1 (0.50) | — | |
| SCHEMBL62201 | 0.74 | — | — | |
| SCHEMBL123985 | 0.74 | CA1 (0.48) | — | |
| SCHEMBL9086872 | 0.74 | MAPT (0.38) | — | |
| SCHEMBL4261664 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092793-A1 | CHROMENE-BASED COMPOUNDS, METHODS AND USES THEREOF | University of Minho (PT) | 2024-03-21 | — | — | US | claimed |
| US-20230035796-A1 | CURCUMINOIDS, ANALOGS THEREOF, AND METHODS OF MAKING THE SAME | WISYS TECHNOLOGY FOUNDATION, INC. | 2023-02-02 | — | — | US | claimed |
| EP-3990118-A1 | CHROMENE-BASED COMPOUNDS, METHODS AND USES THEREOF | Universidade do Minho (PT) | 2022-05-04 | — | — | EP | claimed |
| CN-114026098-A | Benzopyran based compounds, methods and uses thereof | 米尼翁大学 | 2022-02-08 | — | — | CN | claimed |
| CN-110551049-B | Preparation of camphor thiosemicarbazone compound and antitumor activity thereof | 南京林业大学 | 2021-04-20 | — | — | CN | claimed |
| WO-2020261242-A1 | CHROMENE-BASED COMPOUNDS, METHODS AND USES THEREOF | UNIVERSIDADE DO MINHO (PT) | 2020-12-30 | — | — | WO | claimed |
| WO-2020077459-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO, S.E.C. (CA) | 2020-04-23 | — | — | WO | claimed |
| CN-110551049-A | Preparation of camphor thiosemicarbazone compound and antitumor activity thereof | UNIV NANJING FORESTRY | 2019-12-10 | — | — | CN | claimed |
| US-10329249-B1 | Sulindac derivatives | KING SAUD UNIVERSITY (SA) | 2019-06-25 | — | — | US | claimed |
| US-20170079954-A1 | PHARMACEUTICALLY ACCEPTABLE SALTS OF 3,5-DIAMINOPYRAZOLE KINASE INHIBITORS | AXIKIN PHARMACEUTICALS, INC. | 2017-03-23 | — | — | US | claimed |
| US-5510519-A | OPTICAL RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-23 | — | — | US | claimed |
| EP-0508307-B1 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL CO (JP) | 1995-11-29 | — | — | EP | claimed |
| EP-0413528-B1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | YU RUEY J (US) | 1995-11-15 | — | — | EP | claimed |
| US-5298660-A | Compound containing an assymetrical carbon atom | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-29 | — | — | US | claimed |
| US-5231105-A | Ethylamine derivatives and antihypertensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-07-27 | — | — | US | claimed |
| EP-0508307-A2 | Optically active secondary amine compound; process for producing optically active secondary amine compound and process for producing optically active carboxylic acid by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-10-14 | — | — | EP | claimed |
| US-4483861-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-11-20 | — | — | US | claimed |
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | claimed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | claimed |
| EP-0031104-A1 | Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1981-07-01 | — | — | EP | claimed |