Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690514 | 0.84 | EGFR (0.30) | EGFRERBB2 | |
| SCHEMBL4556547 | 0.82 | — | — | |
| Hydrazine SCHEMBL7600144 | 0.81 | — | — | |
| SCHEMBL9000091 | 0.81 | EGFR (0.32) | EGFRERBB2 | |
| SCHEMBL9000086 | 0.79 | — | — | |
| SCHEMBL9000100 | 0.79 | TP53 (0.32) | EGFRERBB2 | |
| Laromustine SCHEMBL2416976 | 0.79 | CA12 (0.30) | — | |
| SCHEMBL7064301 | 0.79 | — | — | |
| SCHEMBL2417510 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL9000096 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6025146-A | — | — | None | — | — | JP | disclosed |
| US-8026395-B1 | Process for the synthesis of anti-neoplasia agent VNP40101M | NANOTHERAPEUTICS, INC. (US) | 2011-09-27 | — | — | US | disclosed |
| EP-0541322-B1 | 1-Alkyl-2-acyl-1,2-disulfonylhydrazines with antineoplastic activity | UNIV YALE (US) | 1996-09-11 | — | — | EP | disclosed |
| JP-H0625146-A | 1-ALKYL-2-ACYL-1,2-DISULFONYLHYDRAZINES | UNIV YALE | 1994-02-01 | — | — | JP | disclosed |
| US-5256820-A | Anticarcinogenic agents | YALE UNIVERSITY (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0541322-A1 | 1-Alkyl-2-acyl-1,2-disulfonylhydrazines with antineoplastic activity | YALE UNIVERSITY (US) | 1993-05-12 | — | — | EP | disclosed |