Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 9/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24855141 | 0.87 | NSD2 (0.56) | NSD2CYP11B1CYP11B2NR3C2PKM | |
| SCHEMBL30800907 | 0.81 | CYP11B1 (0.56) | NSD2CYP11B1CYP11B2NR3C2PDE3B | |
| SCHEMBL24855582 | 0.81 | CYP11B1 (0.56) | NSD2CYP11B1CYP11B2NR3C2PDE3B | |
| SCHEMBL6603981 | 0.78 | CYP11B1 (0.56) | NSD2CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL19188092 | 0.77 | MMP12 (0.62) | NSD2CYP11B1CYP11B2NR3C2PKM | |
| SCHEMBL30494449 | 0.77 | CYP11B1 (0.64) | NSD2CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL26463265 | 0.77 | CYP11B1 (0.64) | NSD2CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL20111135 | 0.77 | GRIA1 (0.79) | CYP11B1CYP11B2PDE3BPDE3AGRIA1 | |
| SCHEMBL6297092 | 0.74 | CYP11B1 (0.64) | NSD2CYP11B1CYP11B2NR3C2PDE3B | |
| SCHEMBL280003 | 0.74 | MMP12 (0.75) | CYP11B1CYP11B2PKMPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023272720-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS OF PD-L1 INTERACTIONS | Ascletis BioScience Co., Ltd (CN) | 2023-01-05 | — | — | WO | disclosed |