Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 6/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24855219 | 0.78 | NSD2 (0.61) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL24855582 | 0.77 | CYP11B1 (0.56) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL30800907 | 0.77 | CYP11B1 (0.56) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL6603273 | 0.76 | BRD4 (0.44) | KMT2AMAPTRXFP1 | |
| SCHEMBL24855141 | 0.76 | NSD2 (0.56) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL19188092 | 0.74 | MMP12 (0.62) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL13932048 | 0.72 | NR3C2 (0.60) | KMT2AMEN1CYP2C19HTTMMP12 | |
| SCHEMBL4258391 | 0.72 | NR3C2 (0.60) | KMT2AMEN1CYP2C19HTTMMP12 | |
| SCHEMBL1120115 | 0.72 | CYP11B1 (1.00) | CYP11B1CYP11B2NSD2PDE3BPDE3A | |
| SCHEMBL30494449 | 0.71 | CYP11B1 (0.64) | CYP11B1CYP11B2NSD2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196412-B1 | NITROGEN CONTAINING HETEROBICYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6716841-B2 | SUCH AS 1-((1-(3-(AMINOMETHYL)PHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-YL)CARBONYL) -5-(2-( AMINOSULFONYL)PHENYL)-2,3-DIHYDRO-1H-INDOLE FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS; ANTICOAGULANTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-04-06 | — | — | US | disclosed |
| US-20030096820-A1 | Nitrogen containing heterobicycles as factor Xa inhibitors | JACOBSON IRINA C (US) | 2003-05-22 | — | — | US | disclosed |
| US-6429205-B1 | ANTICOAGULANTS | BRISTOL-MEYERS SQUIBB PHARMA COMPANY | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096820-A1 | Nitrogen containing heterobicycles as factor Xa inhibitors | SERPINC1, CTRB1, F2 | CYP11B1 1202/4885CYP11B2 2168/4885NSD2 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.