Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008486 | 0.88 | TP53 (0.64) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL20539104 | 0.81 | TSHR (0.62) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL30617438 | 0.81 | TSHR (0.62) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL3790244 | 0.76 | CA1 (0.58) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL31067777 | 0.76 | AMY1A (0.48) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL10612519 | 0.74 | TSHR (0.54) | KDM4EALDH1A1LMNACYP3A4MAPT | |
| SCHEMBL24390319 | 0.74 | AMY1A (0.50) | TP53KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29915706 | 0.74 | AMY1A (0.50) | TP53KDM4EALDH1A1LMNAMAPT | |
| Methoxymethane SCHEMBL10659099 | 0.74 | TSHR (0.59) | TP53KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL19897779 | 0.74 | TRPA1 (0.48) | TP53KDM4EALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019430-A1 | COMPOUNDS AS IMMUNOMODULATORS OF PD-L1 INTERACTIONS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023272720-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS OF PD-L1 INTERACTIONS | Ascletis BioScience Co., Ltd (CN) | 2023-01-05 | — | — | WO | disclosed |