SCHEMBL248573

SCHEMBL248573

C=CCc1cccc(Cl)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.56
TAAR1 Q96RJ0 1/20 0.50
IDO1 P14902 2/20 0.48
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
CYP2A13 Q16696 2/20 0.41
TSHR P16473 1/20 0.38
HPGD P15428 1/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
AKR1B1 P15121 1/20 0.38
DBH P09172 1/20 0.38
GRIN1 Q05586 1/20 0.37
GRIN2B Q13224 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248417 0.82 IDO1 (0.50) PNMTTAAR1IDO1GABRA1GABRB2
SCHEMBL29473927 0.82 IDO1 (0.50) PNMTTAAR1IDO1GABRA1GABRB2
Hydrochloric Acid SCHEMBL11666235 0.80 IDO1 (0.48) PNMTTAAR1IDO1GABRA1GABRB2
SCHEMBL9275883 0.80 IDO1 (0.48) PNMTTAAR1IDO1GABRA1GABRB2
SCHEMBL7499710 0.79 GABRA1 (0.46) PNMTTAAR1IDO1GABRA1GABRB2
SCHEMBL7499705 0.79 GABRA1 (0.46) PNMTTAAR1IDO1GABRA1GABRB2
SCHEMBL1908482 0.79 GABRA1 (0.66) GABRA1GABRB2ALDH1A1KDM4EHPGD
SCHEMBL7696946 0.79 GABRA1 (0.46) PNMTGABRA1GABRB2ALDH1A1KDM4E
SCHEMBL2364383 0.79 GABRA1 (0.55) GABRA1GABRB2ALDH1A1KDM4EPOLB
SCHEMBL7499718 0.79 GABRA1 (0.46) PNMTTAAR1IDO1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3951614-A REACTION PRODUCT OF A HYDROCARBYL AMINE AND POLYFUNCTIONAL COUPLING AGENT CHEVRON RESEARCH COMPANY (US) 1976-04-20 US claimed
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
CN-112979917-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2023-04-25 CN disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
CN-109790269-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2022-06-14 CN disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
WO-2013100567-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN ALLEVIATING OR TREATING PAIN AND NEUROPATHIC PAIN BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
WO-2013100570-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILESY BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
WO-2013100569-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed
EP-2590936-A2 PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME Bio-Pharm Solutions Co., Ltd. (KR) 2013-05-15 EP disclosed
WO-2012096458-A2 PROCESS FOR PREPARATION OF PHENYL CARBAMATE DERIVATIVES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2012-07-19 WO disclosed
WO-2012002773-A2 PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2012-01-05 WO disclosed
US-5030777-A Synthesis of 3,5-dichloroalkylbenzene and recovery of 1,3-dichlorobenzene STANDARD CHLORINE OF DELAWARE, INC. (US) 1991-07-09 US disclosed
EP-0115985-B1 PROCESS FOR THE ALKYLATION OF HALOGENATED AND/OR TRIFLUORMETHYLATED BENZENEDERIVATIVES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-12-18 EP disclosed
EP-0115985-A1 Process for the alkylation of halogenated and/or trifluormethylated benzenederivatives RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-08-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B PNMT 2353/4885TAAR1 4327/4885IDO1 65/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B PNMT 2212/4885TAAR1 4155/4885IDO1 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.