SCHEMBL7696946

SCHEMBL7696946

C=CCc1cccc(C=C)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
ALDH1A1 P00352 3/20 0.43
AKR1B1 P15121 1/20 0.39
KMT2A Q03164 6/20 0.39
MEN1 O00255 5/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 4/20 0.36
GAA P10253 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CASP1 P29466 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX12 P18054 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
MAPK1 P28482 1/20 0.34
PNMT P11086 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810324 0.82 ALDH1A1 (0.45) GABRA1GABRB2ALDH1A1PNMT
SCHEMBL1486004 0.80 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1LMNAPNMT
SCHEMBL16953041 0.80 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1PNMT
SCHEMBL248573 0.79 PNMT (0.56) GABRA1GABRB2ALDH1A1AKR1B1MAPT
SCHEMBL30679 0.79 GABRA1 (0.47) GABRA1GABRB2ALDH1A1AKR1B1KMT2A
SCHEMBL16960550 0.78 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1LMNAL3MBTL1
SCHEMBL7219053 0.78 GABRA1 (0.47) GABRA1GABRB2ALDH1A1AKR1B1KMT2A
SCHEMBL1123438 0.78 GABRA1 (0.47) GABRA1GABRB2ALDH1A1AKR1B1KMT2A
SCHEMBL16957146 0.77 ALDH1A1 (0.41) ALDH1A1MAPTKDM4EHSD17B10PNMT
Methane SCHEMBL28621463 0.77 GABRA1 (0.45) GABRA1GABRB2ALDH1A1AKR1B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6353070-B1 STAR POLYMER OBTAINED BY POLYMERIZING VINYLAROMATIC MONOMER AND BRANCHING MONOMER CONTAINING AT LEAST TWO VINYLAROMATIC RADICALS IN PRESENCE OF CATALYST COMPRISING TRANSITION METAL COMPLEX, CATION-FORMING AGENT, OPTIONAL ALUMINUM COMPOUND BASF AKTIENGESELLSCHAFT (DE) 2002-03-05 US disclosed
US-6303806-B2 TITANIUM COMPOUNDS AS BRANCHING MONOMER UNITS BASF AKTIENGESELLSCHAFT (DE) 2001-10-16 US disclosed
US-20010009966-A1 Star polymers, and their preparation WUNSCH JOSEF (DE) 2001-07-26 US disclosed
US-6235838-B1 USING STYRENE/DIPHENYLETHYLENE-DIENE BLOCK COPOLYMERS AS DISPERSING AUXILIARIES. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
US-4049596-A Corrosion resistant aqueous and solvent-based primer compositions containing synergistic blends of zinc borate and barium metaborate pigments PPG INDUSTRIES, INC. (US) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010009966-A1 Star polymers, and their preparation MYB, PICALM, VMA21 GABRA1 1158/4885GABRB2 2289/4885ALDH1A1 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.