SCHEMBL24857368

SCHEMBL24857368

CC(C)c1cc(Cl)cn2ccnc12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
HTR3A P46098 1/20 0.37
NUDT1 P36639 1/20 0.33
GCGR P47871 1/20 0.31
TNKS O95271 1/20 0.31
MDM2 Q00987 1/20 0.31
AURKA O14965 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25749124 0.81 L3MBTL1 (0.42) L3MBTL1GABRA1NUDT1TNKS
SCHEMBL24198026 0.81 L3MBTL1 (0.46) L3MBTL1NUDT1TNKS
SCHEMBL24857557 0.79 L3MBTL1 (0.41) L3MBTL1NUDT1TNKS
SCHEMBL16705075 0.77 L3MBTL1 (0.62) L3MBTL1HTR3ANUDT1TNKS
SCHEMBL22490650 0.76 L3MBTL1 (0.43) L3MBTL1HTR3ANUDT1TNKSAURKA
SCHEMBL14006669 0.74 NUDT1 (0.47) L3MBTL1HTR3ANUDT1AURKA
SCHEMBL6370588 0.74 L3MBTL1 (0.42) L3MBTL1HTR3ANUDT1TNKSAURKA
SCHEMBL25974824 0.73 L3MBTL1 (0.41) L3MBTL1HTR3ANUDT1TNKSAURKA
SCHEMBL1983144 0.73 L3MBTL1 (0.49) L3MBTL1HTR3ANUDT1TNKSAURKA
SCHEMBL20125020 0.72 L3MBTL1 (0.41) L3MBTL1NUDT1TNKSKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002414-A1 AZAHETEROARYL COMPOUND AND APPLICATION THEREOF SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002414-A1 AZAHETEROARYL COMPOUND AND APPLICATION THEREOF EZH2, EED, SUZ12 L3MBTL1 3524/4885GABRA1 1181/4885GABRB1 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.