Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24857525 | 0.80 | L3MBTL1 (0.47) | L3MBTL1TNKSNUDT1KDM4EALDH1A1 | |
| SCHEMBL24857448 | 0.79 | L3MBTL1 (0.42) | L3MBTL1TNKSNUDT1KDM4EALDH1A1 | |
| SCHEMBL16705075 | 0.78 | L3MBTL1 (0.62) | L3MBTL1TNKSHTR3ANUDT1KDM4E | |
| SCHEMBL22490650 | 0.77 | L3MBTL1 (0.43) | L3MBTL1TNKSHTR3ANUDT1AURKA | |
| SCHEMBL14006669 | 0.76 | NUDT1 (0.47) | L3MBTL1HTR3ANUDT1ALDH1A1GAA | |
| SCHEMBL25974824 | 0.74 | L3MBTL1 (0.41) | L3MBTL1TNKSHTR3ANUDT1AURKA | |
| SCHEMBL1983144 | 0.74 | L3MBTL1 (0.49) | L3MBTL1TNKSHTR3ANUDT1ALDH1A1 | |
| SCHEMBL24857368 | 0.74 | L3MBTL1 (0.41) | L3MBTL1TNKSHTR3ANUDT1AURKA | |
| SCHEMBL15828609 | 0.74 | TNKS (0.43) | L3MBTL1TNKSNUDT1KDM4EALDH1A1 | |
| SCHEMBL10135729 | 0.74 | L3MBTL1 (0.41) | L3MBTL1TNKSHTR3ANUDT1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
| US-9029377-B2 | Platelet-activating factor receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20120108595-A1 | PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LLC | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108595-A1 | PLATELET-ACTIVATING FACTOR RECEPTOR ANTAGONISTS | PTAFR, PAFAH1B2, PAFAH1B3 | L3MBTL1 4449/4885TNKS 457/4885HTR3A 1463/4885 |
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | EZH2, EED, SUZ12 | L3MBTL1 3524/4885TNKS 2280/4885HTR3A 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.