Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 19/20 | 0.42 |
| ▸ | JAK3 | P52333 | 19/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 11/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23030108 | 0.78 | JAK2 (0.56) | JAK2JAK3PTK2 | |
| SCHEMBL24857423 | 0.78 | KDM4E (0.35) | JAK2JAK3PTK2 | |
| SCHEMBL21078019 | 0.77 | JAK2 (0.57) | JAK2JAK3PTK2 | |
| SCHEMBL24857430 | 0.74 | LMNA (0.34) | JAK2JAK3PTK2 | |
| SCHEMBL22428661 | 0.69 | PSEN1 (0.54) | JAK2JAK3PTK2 | |
| SCHEMBL22428595 | 0.68 | PSEN1 (0.55) | JAK2JAK3PTK2 | |
| SCHEMBL22428597 | 0.68 | PSEN1 (0.55) | JAK2JAK3PTK2 | |
| SCHEMBL16840469 | 0.67 | JAK2 (0.64) | JAK2JAK3PTK2 | |
| SCHEMBL23421751 | 0.66 | CA2 (0.33) | — | |
| SCHEMBL10256411 | 0.66 | MAP4K4 (0.46) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002414-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | EZH2, EED, SUZ12 | JAK2 447/4885JAK3 1147/4885PTK2 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.