Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20868507 | 0.85 | NCF1 (0.60) | KDM4EALDH1A1NCF1WNT3ARORC | |
| SCHEMBL23059522 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1NCF1WNT3ARORC | |
| SCHEMBL22358618 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1NCF1WNT3ARORC | |
| SCHEMBL617426 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1WNT3AKMT2AMEN1 | |
| SCHEMBL20868221 | 0.80 | HTR2A (0.55) | KDM4EALDH1A1WNT3AKMT2AMEN1 | |
| SCHEMBL12551052 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1NCF1WNT3ARORC | |
| SCHEMBL10066949 | 0.79 | ALDH1A1 (0.57) | KDM4EALDH1A1WNT3ARORCKMT2A | |
| Hydrochloric Acid SCHEMBL20857074 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1NCF1WNT3ARORC | |
| SCHEMBL19245039 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1WNT3ARORCKMT2A | |
| SCHEMBL12551054 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1WNT3ARORCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230003706-A1 | METHODS OF EVALUATING SMALL MOLECULE-MODIFIED POLYMERS IN COMPOSITIONS | SIGILON THERAPEUTICS, INC. | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230003706-A1 | METHODS OF EVALUATING SMALL MOLECULE-MODIFIED POLYMERS IN COMPOSITIONS | FN1, MFAP1, FIBP | KDM4E 1950/4885ALDH1A1 3217/4885NCF1 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.