SCHEMBL24858788

SCHEMBL24858788

CC(=O)/C=C(/C)Oc1ccccc1-c1ccccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.43
BAZ2B Q9UIF8 2/20 0.41
BRD4 O60885 2/20 0.41
BRD2 P25440 1/20 0.41
BRD3 Q15059 1/20 0.41
BAZ2A Q9UIF9 1/20 0.41
PDE5A O76074 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 4/20 0.38
PKM P14618 2/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5322046 0.83 PDE5A (0.53) GRM4BAZ2BBRD4BRD2BRD3
SCHEMBL4705063 0.77 GRM4 (0.48) GRM4BAZ2BBRD4BRD2BRD3
Dipyridyl SCHEMBL8776253 0.72 KDM4E (0.52) BAZ2BBRD4BRD2BRD3BAZ2A
SCHEMBL2039527 0.71 SMN1; SMN2 (0.62) PDE5AADRA2AADRA2BADRA2CADRA1D
SCHEMBL29496935 0.71 SMN1; SMN2 (0.62) PDE5AADRA2AADRA2BADRA2CADRA1D
SCHEMBL7196588 0.70 KDM4E (0.54) GRM4ADRA2AADRA2BADRA2CADRA1D
SCHEMBL18228878 0.70 ADRA2A (0.46) GRM4BRD4ADRA2AADRA2BADRA2C
SCHEMBL28129241 0.70 ADRA1D (0.46) GRM4BRD4ADRA2AADRA2BADRA2C
SCHEMBL9459615 0.70 KMT2A (0.54) GRM4BAZ2BBRD4BRD2BRD3
SCHEMBL27667292 0.70 KDM4E (0.50) GRM4BAZ2BBRD4BRD2BRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552261-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552261-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP GRM4 3531/4885BAZ2B 4805/4885BRD4 3217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.