SCHEMBL24860210

SCHEMBL24860210

C=C(/N=C(\C)c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.48
MAPT P10636 3/20 0.48
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
WDR5 P61964 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24443126 0.98 MAPT (0.47) SMN1; SMN2MAPTALDH1A1POLBL3MBTL1
SCHEMBL16373659 0.98 MAPT (0.47) SMN1; SMN2MAPTALDH1A1POLBL3MBTL1
SCHEMBL21600414 0.90 MAPT (0.43) SMN1; SMN2MAPTALDH1A1POLBL3MBTL1
SCHEMBL16364863 0.88 LMNA (0.45) SMN1; SMN2MAPTALDH1A1POLBL3MBTL1
SCHEMBL22448436 0.86 MAPT (0.39) SMN1; SMN2MAPTALDH1A1POLBL3MBTL1
SCHEMBL24860142 0.84 MAPT (0.39) SMN1; SMN2MAPTALDH1A1POLBL3MBTL1
SCHEMBL23816806 0.84 KMO (0.42) SMN1; SMN2MAPTALDH1A1CYP1A2CYP2D6
SCHEMBL19421378 0.82 SMN1; SMN2 (0.43) SMN1; SMN2MAPTALDH1A1POLBNPC1
SCHEMBL22898732 0.82 MAPT (0.34) SMN1; SMN2MAPTALDH1A1POLBNPC1
SCHEMBL18901095 0.81 SMN1; SMN2 (0.36) SMN1; SMN2MAPTALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552258-B2 Organic light-emitting device comprising emission layer satisfying specific singlet excitation energy level conditions SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552258-B2 Organic light-emitting device comprising emission layer satisfying specific singlet excitation energy level conditions EML4, NES, TBL2 SMN1; SMN2 1179/4885MAPT 141/4885ALDH1A1 1062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.