Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 13/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.40 |
| ▸ | NPY1R | P25929 | 8/20 | 0.40 |
| ▸ | NPY2R | P49146 | 5/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886040 | 0.90 | FOLH1 (0.47) | F2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL18250195 | 0.89 | NPY4R (0.39) | F2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL16656670 | 0.89 | NPY4R (0.40) | NPY4RNPY5RNPY1RNPY2RALB | |
| SCHEMBL15354283 | 0.88 | NPY4R (0.38) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL12035268 | 0.87 | NPY4R (0.46) | F2NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL14615959 | 0.86 | SIRT6 (0.44) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL20631639 | 0.85 | NPY4R (0.38) | NPY4RNPY5RNPY1RNPY2RALB | |
| SCHEMBL24157931 | 0.85 | NPY4R (0.40) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL18264761 | 0.84 | NPY4R (0.46) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL16501504 | 0.83 | NOD1 (0.49) | NPY4RNPY5RNPY1RNPY2RSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3408271-B1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMA (US) | 2023-01-11 | — | — | EP | disclosed |