Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24860342 | 0.90 | F2 (0.41) | FOLH1F2ALBNPY4RNPY1R | |
| SCHEMBL30413729 | 0.89 | C3AR1 (0.52) | FOLH1C3AR1NOD1F2GNPAT | |
| SCHEMBL10314456 | 0.88 | GNPAT (0.42) | FOLH1F2GNPATNPY4RNPY1R | |
| SCHEMBL19975767 | 0.87 | SIRT6 (0.48) | FOLH1C3AR1NOD1GNPATALB | |
| SCHEMBL446929 | 0.87 | FOLH1 (0.49) | FOLH1C3AR1NOD1GNPATALB | |
| SCHEMBL30526285 | 0.87 | FOLH1 (0.49) | FOLH1C3AR1NOD1GNPATALB | |
| SCHEMBL6026003 | 0.87 | FOLH1 (0.49) | FOLH1C3AR1NOD1GNPATALB | |
| SCHEMBL468901 | 0.87 | FOLH1 (0.49) | FOLH1C3AR1NOD1GNPATALB | |
| SCHEMBL15757149 | 0.86 | C3AR1 (0.42) | FOLH1C3AR1NOD1GNPATNPY4R | |
| SCHEMBL15757154 | 0.86 | C3AR1 (0.42) | FOLH1C3AR1NOD1GNPATNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023860-B2 | Pro-drugs for controlled release of biologically active compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | claimed |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | SIGNATURE THERAPEUTICS, INC. | 2012-06-07 | — | — | US | claimed |
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 3I, LP | 2009-05-28 | — | — | US | claimed |
| WO-2008101202-A1 | N-17-ALKYLATED PRODRUGS OF OPIOIDS | PHARMACOFORE, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| CN-116813705-A | Peptide compound, application thereof and composition containing peptide compound | 凯惠科技发展(上海)有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109206481-B | Peptide compound, application thereof and composition containing peptide compound | 尚华医药科技(江西)有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615436-A | Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide | 中国医学科学院药物研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-114573686-A | Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof | 中国医学科学院药物研究所 | 2022-06-03 | — | — | CN | disclosed |
| US-9023860-B2 | Pro-drugs for controlled release of biologically active compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | SIGNATURE THERAPEUTICS, INC. | 2012-06-07 | — | — | US | disclosed |
| US-20110105381-A2 | Prodrugs of Peripheral Phenolic Opioid Antagonists | PHARMACOFORE, INC. (US) | 2011-05-05 | — | — | US | disclosed |
| US-20100267614-A1 | Prodrugs of Peripheral Phenolic Opioid Antagonists | PHARMACOFORE, INC. | 2010-10-21 | — | — | US | disclosed |
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 3I, LP | 2009-05-28 | — | — | US | disclosed |
| WO-2008101187-A2 | PRO-DRUGS OF PERIPHERAL PHENOLIC OPIOID ANTAGONISTS | PHARMACOFORE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008101202-A1 | N-17-ALKYLATED PRODRUGS OF OPIOIDS | PHARMACOFORE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | CRH, FURIN, PEPD | FOLH1 747/4885C3AR1 2726/4885NOD1 4616/4885 |
| US-20110105381-A2 | Prodrugs of Peripheral Phenolic Opioid Antagonists | OPRM1, OPRL1, OPRK1 | FOLH1 1970/4885C3AR1 301/4885NOD1 1290/4885 |
| US-20120142718-A1 | N-17-Alkylated Prodrugs of Opioids | OPRM1, OPRD1, OPRL1 | FOLH1 2504/4885C3AR1 267/4885NOD1 3384/4885 |
| US-20100267614-A1 | Prodrugs of Peripheral Phenolic Opioid Antagonists | OPRM1, OPRK1, OPRL1 | FOLH1 1959/4885C3AR1 275/4885NOD1 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.