Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903881 | 0.86 | LMNA (0.46) | MAPK1TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL1260575 | 0.76 | HMGCR (0.41) | BPTFMAPK1TSHRLMNANCOA1 | |
| SCHEMBL27906024 | 0.74 | MAPK1 (0.53) | BPTFMAPK1TSHRLMNASMN1; SMN2 | |
| SCHEMBL23846429 | 0.73 | TSHR (0.45) | BPTFMAPK1TSHRLMNASMN1; SMN2 | |
| SCHEMBL8961617 | 0.72 | BPTF (0.61) | BPTFMAPK1TSHRLMNASMN1; SMN2 | |
| SCHEMBL11811861 | 0.72 | TSHR (0.47) | BPTFTSHRLMNASMN1; SMN2NCOA1 | |
| SCHEMBL28716765 | 0.71 | TSHR (0.62) | BPTFMAPK1TSHRLMNASMN1; SMN2 | |
| SCHEMBL11053816 | 0.71 | ALOX5 (0.43) | MAPK1TSHRNCOA1NCOA3KDM4E | |
| SCHEMBL159393 | 0.71 | MAPT (0.54) | LMNAHTTKDM4EMAPTPOLB | |
| SCHEMBL24792666 | 0.71 | MAPK1 (0.56) | BPTFMAPK1TSHRSMN1; SMN2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772005-B2 | Laccases, compositions and methods of use | DANISCO US INC. (US) | 2014-07-08 | — | — | US | claimed |
| US-20120151682-A1 | Novel Laccases, Compositions and Methods of Use | DANISCO US INC. (US) | 2012-06-21 | — | — | US | claimed |
| EP-2094842-B1 | NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE | DANISCO US INC (US) | 2012-06-13 | — | — | EP | claimed |
| EP-2094842-A2 | NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE | Danisco US, INC., Genencor Division (US) | 2009-09-02 | — | — | EP | claimed |
| US-20080196173-A1 | Novel Laccases, Compositions And Methods of Use | DANISCO US INC., GENENCOR DIVISION | 2008-08-21 | — | — | US | claimed |
| WO-2008076322-A2 | NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE | DANISCO US, INC., GENENCOR DIVISION (US) | 2008-06-26 | — | — | WO | claimed |
| EP-2376629-A1 | LACCASES AND METHODS OF USE THEREOF AT LOW TEMPERATURE | Danisco US Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010075402-A1 | LACCASES AND METHODS OF USE THEREOF AT LOW TEMPERATURE | DANISCO US INC. (US) | 2010-07-01 | — | — | WO | disclosed |