Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694279 | 0.76 | DGAT1 (0.41) | LMNAHTT | |
| SCHEMBL8593509 | 0.76 | TSHR (0.44) | TSHRLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL30526948 | 0.74 | TSHR (0.44) | TSHRLMNAHTTBPTFMAPK1 | |
| SCHEMBL27856987 | 0.73 | DGAT1 (0.39) | TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL2486086 | 0.73 | BPTF (0.49) | TSHRLMNAHTTBPTFMAPK1 | |
| SCHEMBL6644694 | 0.72 | MAPT (0.38) | LMNAHTTMAPK1PARP10PARP15 | |
| SCHEMBL4514123 | 0.72 | DGAT1 (0.41) | TSHR | |
| SCHEMBL3337229 | 0.71 | ROCK2 (0.38) | TSHRLMNAHTTPARP10MEN1 | |
| SCHEMBL4512580 | 0.71 | DGAT1 (0.38) | TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL4753814 | 0.71 | ALDH1A1 (0.39) | TSHRLMNAHTTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188880-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |