Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23974745 | 0.83 | SLC6A3 (0.38) | HTTKMT2ASLC6A3PTPRCABCG2 | |
| SCHEMBL24896043 | 0.80 | HTT (0.40) | HTTKMT2ASLC6A3PTPRCHSD17B3 | |
| SCHEMBL18566642 | 0.76 | ABCG2 (0.51) | HTTKMT2ASLC6A3ABCG2ATM | |
| SCHEMBL22005386 | 0.75 | ALDH1A1 (0.39) | HTTKMT2ASLC6A3PTPRCATM | |
| SCHEMBL26551052 | 0.73 | MEN1 (0.34) | KMT2AALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL2482051 | 0.73 | NR4A2 (0.54) | HTTSLC6A3ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19774227 | 0.71 | KMT2A (0.35) | HTTKMT2ASLC6A3PTPRCABCG2 | |
| SCHEMBL18165288 | 0.71 | HDAC8 (0.50) | HTTKMT2ASLC6A3ABCG2ALDH1A1 | |
| SCHEMBL21102389 | 0.70 | HDAC8 (0.49) | HTTKMT2ASLC6A3ABCG2ATM | |
| SCHEMBL7656620 | 0.69 | SLC6A3 (0.61) | HTTKMT2ASLC6A3HSD17B3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4116297-A1 | CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING | SFC Co., Ltd. (KR) | 2023-01-11 | — | — | EP | disclosed |