Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542007 | 0.85 | SLC6A3 (0.61) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| Dimethyl Phthalate SCHEMBL29269027 | 0.84 | ALDH1A1 (0.56) | SLC6A3ALDH1A1GAAHTTKMT2A | |
| SCHEMBL21102391 | 0.84 | SLC6A3 (0.60) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL21102274 | 0.84 | SLC6A3 (0.60) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL6437163 | 0.84 | SLC6A3 (0.59) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL2482051 | 0.84 | NR4A2 (0.54) | SLC6A3ALDH1A1GAAHTTTSHR | |
| SCHEMBL7662247 | 0.82 | ALDH1A1 (0.51) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL3168568 | 0.81 | SLC6A3 (0.65) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL21102272 | 0.81 | SLC6A3 (0.65) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 | |
| SCHEMBL21102267 | 0.81 | SLC6A3 (0.52) | SLC6A3ALDH1A1GAASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |