Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754930 | 0.73 | GPR84 (0.38) | GPR84PARP15PARP10MAOBKCNH2 | |
| SCHEMBL752324 | 0.71 | GPR84 (0.37) | GPR84MAOBSCN3AKCNH2HPD | |
| SCHEMBL2487611 | 0.70 | JAK2 (0.46) | MAOB | |
| SCHEMBL2488805 | 0.64 | ALKBH1 (0.42) | — | |
| SCHEMBL12420849 | 0.62 | KDM5A (0.62) | PARP15PARP10MAOBHDAC6PARP14 | |
| SCHEMBL10314927 | 0.62 | GRM5 (0.65) | GPR84MAOBKCNH2PDE4A | |
| SCHEMBL4677019 | 0.60 | MAOB (0.48) | PARP15PARP10MAOBSCN3APARP14 | |
| SCHEMBL30973177 | 0.60 | GRM2 (0.47) | PARP15PARP10MAOBEGFR | |
| SCHEMBL13806483 | 0.60 | KDM5A (0.47) | PARP15PARP10MAOBHDAC6PARP14 | |
| SCHEMBL2014419 | 0.59 | GRM5 (0.53) | GPR84PARP15PARP10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181985-B1 | Antiviral Agent | SHIONOGI & CO (JP) | 2011-10-26 | — | — | EP | disclosed |