SCHEMBL754930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752324	0.87	GPR84 (0.37)	GPR84PDE4AMEN1KMT2ACYP1A2
	SCHEMBL755973	0.85	PKM (0.41)	LIPGALDH1A1
	SCHEMBL753011	0.83	JAK2 (0.45)	LIPGMAOB
	SCHEMBL752750	0.78	NPC1 (0.50)	GPR84LIPGCYP1A2CYP2C9CYP2C19
	SCHEMBL754565	0.77	LIPG (0.35)	LIPGALDH1A1SMN1; SMN2
	SCHEMBL2486304	0.73	GPR84 (0.36)	GPR84PDE4AMAOBKCNH2PARP15
	SCHEMBL756220	0.72	JAK2 (0.43)	LIPGMAOBKCNH2
	SCHEMBL751416	0.72	JAK2 (0.44)	LIPGMEN1KMT2AMAOBALDH1A1
	SCHEMBL755319	0.71	JAK2 (0.43)	LIPGKMT2AMAOBALDH1A1SMN1; SMN2
	SCHEMBL754587	0.71	JAK2 (0.41)	LIPGCYP1A2CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.