SCHEMBL24863352

SCHEMBL24863352

O=C(CCc1c[nH]c2ccccc12)N/N=C/c1ccc2nccnc2c1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.70
ARHGEF12 Q9NZN5 1/20 0.69
MAPT P10636 9/20 0.67
POLB P06746 5/20 0.67
KMT2A Q03164 4/20 0.67
MEN1 O00255 3/20 0.67
THRB P10828 1/20 0.67
ALDH1A1 P00352 5/20 0.65
KDM4E B2RXH2 3/20 0.65
GFER P55789 1/20 0.65
TRPM5 Q9NZQ8 1/20 0.55
LMNA P02545 1/20 0.54
RAD52 P43351 1/20 0.54
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
GAA P10253 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
GLA P06280 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393675 0.83 FAAH (1.00) FAAHMAPTPOLBKMT2AMEN1
SCHEMBL20175987 0.82 ARHGEF12 (1.00) FAAHARHGEF12MAPTPOLBKMT2A
SCHEMBL15936925 0.82 ARHGEF12 (1.00) FAAHARHGEF12MAPTPOLBKMT2A
SCHEMBL19665210 0.82 ARHGEF12 (1.00) FAAHARHGEF12MAPTPOLBKMT2A
SCHEMBL17603571 0.82 ARHGEF12 (1.00) FAAHARHGEF12MAPTPOLBKMT2A
SCHEMBL29372342 0.82 ARHGEF12 (1.00) FAAHARHGEF12MAPTPOLBKMT2A
SCHEMBL393680 0.81 FAAH (0.83) FAAHMAPTPOLBKMT2AMEN1
SCHEMBL395281 0.81 FAAH (0.83) FAAHMAPTPOLBKMT2AMEN1
Hydrochloric Acid SCHEMBL31717447 0.81 ARHGEF12 (0.98) FAAHARHGEF12MAPTPOLBKMT2A
Hydrochloric Acid SCHEMBL29557944 0.81 ARHGEF12 (0.98) FAAHARHGEF12MAPTPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4116290-A1 PLATELET STORAGE METHODS AND COMPOSITIONS FOR SAME Platefuse, Inc. (US) 2023-01-11 EP disclosed