Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | GFER | P55789 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395281 | 0.91 | FAAH (0.83) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL393680 | 0.91 | FAAH (0.83) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL393500 | 0.88 | MAPT (0.81) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL393998 | 0.88 | FAAH (0.78) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL395724 | 0.87 | FAAH (0.76) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL391199 | 0.87 | FAAH (0.76) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL394413 | 0.84 | FAAH (0.72) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24863352 | 0.83 | FAAH (0.70) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4075701 | 0.83 | SMN1; SMN2 (0.82) | FAAHMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4075698 | 0.83 | SMN1; SMN2 (0.82) | FAAHMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101649-B2 | N-acylhydrazone derivatives useful as modulators of nicotinic acetylcholine receptors | NEUROSEARCH A/S (DK) | 2012-01-24 | — | — | US | disclosed |