SCHEMBL248639

SCHEMBL248639

C=Cc1ccc(F)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TP53 P04637 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
TRPA1 O75762 2/20 0.38
PLA2G7 Q13093 2/20 0.38
RAB9A P51151 2/20 0.38
PABPC1 P11940 1/20 0.38
EIF4H Q15056 1/20 0.38
TSHR P16473 1/20 0.38
HDAC8 Q9BY41 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
PTGS2 P35354 1/20 0.35
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29662132 1.00 NFE2L2 (0.50) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL28947606 0.93 NFE2L2 (0.45) NFE2L2ALDH1A1TP53LMNAMAPT
Bicarbonate SCHEMBL28992540 0.89 PLA2G7 (0.45) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL29603833 0.87 NFE2L2 (0.41) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL28734149 0.87 NFE2L2 (0.41) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL18785322 0.81 NFE2L2 (0.37) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL11725687 0.80 ALDH1A1 (0.46) NFE2L2ALDH1A1TP53MAPTTDP1
SCHEMBL16953596 0.80 NFE2L2 (0.47) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL22869168 0.80 ALDH1A1 (0.46) NFE2L2ALDH1A1TP53LMNAMAPT
SCHEMBL9900747 0.80 HTR2A (0.40) NFE2L2LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040661-A Ultra-high temperature retarder for well cementation cement and preparation method thereof 古莱特科技股份有限公司 2025-05-27 CN claimed
CN-119662577-A A preparation method Ticagrelor intermediate styrene monooxygenase mutants of the body 中国科学院成都生物研究所 2025-03-21 CN claimed
CN-119220146-A Novel heat-insulating paint 山东三佳聚合高分子材料有限公司 2024-12-31 CN claimed
CN-118895034-A Nano-modified pressure-resistant reinforced epoxy glass fiber composite material with fluorine conjugated structure 西安交通大学 2024-11-05 CN claimed
CN-118290648-A Preparation method and application of acrylate emulsion for water-based strippable coating 万华化学集团股份有限公司 2024-07-05 CN claimed
CN-111979629-B Processing method of special carbon fiber fabric for special clothing 安徽宜民服饰股份有限公司 2023-08-25 CN claimed
CN-115975462-A Building surface composite nano inner film-forming waterproof layer and preparation method thereof 广州全系新材料股份有限公司 2023-04-18 CN claimed
CN-112500513-B Preparation system and process of alpha olefin-fluorostyrene polymer 南京延长反应技术研究院有限公司 2022-12-16 CN claimed
CN-111978455-B Hydrophobic fluorine modified acrylic emulsion and preparation method and application thereof 临沂普立玛新材料有限公司 2022-10-28 CN claimed
CN-113136001-B Preparation method of ethylene-fluorostyrene copolymer 中国科学院长春应用化学研究所 2022-05-06 CN claimed
CN-108586221-B Intermediate for preparing ticagrelor and preparation method thereof 常州制药厂有限公司 2021-03-02 CN claimed
CN-107722155-B Alpha olefin-fluorostyrene polymer and preparation method thereof 中国科学院长春应用化学研究所 2021-01-08 CN claimed
CN-111978455-A Hydrophobic fluorine modified acrylic emulsion and preparation method and application thereof 临沂普立玛新材料有限公司 2020-11-24 CN claimed
CN-111979629-A Processing method of special carbon fiber fabric for special clothing 安徽宜民服饰股份有限公司 2020-11-24 CN claimed
CN-109956916-A A kind of method preparing (S) -2- (3,4- difluorophenyl) ethylene oxide 乐山职业技术学院 2019-07-02 CN claimed
CN-108586221-A It is used to prepare the intermediate and preparation method thereof of Ticagrelor 常州制药厂有限公司 2018-09-28 CN claimed
CN-106631887-B A kind of preparation technology of (1R, 2S) 1 cyano group 2 (3,4 difluorophenyl) cyclopropane 杨绮红 2018-03-20 CN claimed
CN-107722155-A A kind of alhpa olefin fluorobenzene ethene polymer and preparation method thereof 中国科学院长春应用化学研究所 2018-02-23 CN claimed
CN-106631887-A Preparation process for (1R,2S)-1-cyano-2-(3,4-difluoro-phenyl)cyclopropane 青岛云天生物技术有限公司 2017-05-10 CN claimed
CN-102317333-A Acrylic resin composition, and optical film comprising same LG CHEMICAL LTD 2012-01-11 CN claimed