Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864552 | 0.86 | KDM4E (0.39) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL24864285 | 0.82 | KDM4E (0.45) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL22623445 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL10246348 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL23451094 | 0.69 | MAPT (0.59) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL17267121 | 0.69 | MTNR1A (0.38) | ALDH1A1KDM4EKISS1RMTNR1AMTNR1B | |
| SCHEMBL13611402 | 0.69 | MAPT (0.59) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL15984442 | 0.68 | CYP2C9 (0.41) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14577009 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14577008 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |