Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833165 | 0.88 | LMNA (0.37) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL21008353 | 0.88 | TSHR (0.35) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL19704493 | 0.84 | TSHR (0.42) | LMNAKDM4EALDH1A1 | |
| SCHEMBL31155390 | 0.81 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1 | |
| SCHEMBL17833164 | 0.74 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL19707949 | 0.74 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4E | |
| E968 SCHEMBL2723809 | 0.73 | LMNA (0.67) | LMNAL3MBTL1TDP1KDM4ETHRB | |
| E968 SCHEMBL6729753 | 0.73 | — | — | |
| E968 SCHEMBL17062 | 0.73 | — | — | |
| E968 SCHEMBL17766 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |