Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602173 | 0.79 | ADRB2 (0.46) | ADRB2HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL29624902 | 0.79 | KDM4E (0.38) | ADRB2HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL29334761 | 0.78 | MEN1 (0.36) | ADRB2HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL27291304 | 0.77 | MEN1 (0.39) | ADRB2HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL854679 | 0.75 | USP2 (0.48) | MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL29344226 | 0.75 | LMNA (0.33) | HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL10550726 | 0.74 | KDM4E (0.41) | ADRB2KDM4EADRB1ADRB3ATM | |
| SCHEMBL29334481 | 0.72 | MEN1 (0.32) | ADRB2HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL16088019 | 0.71 | MEN1 (0.36) | ADRB2HTR1AMEN1KMT2AKDM4E | |
| SCHEMBL24864338 | 0.71 | BLM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151890-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |