Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550726 | 0.96 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL20739180 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2ADRB2KMT2A | |
| SCHEMBL16948554 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2ADRB2MEN1 | |
| SCHEMBL8602173 | 0.81 | ADRB2 (0.46) | KDM4EADRB2MEN1KMT2AHTR1A | |
| SCHEMBL27291304 | 0.80 | MEN1 (0.39) | KDM4EADRB2MEN1KMT2AADRB1 | |
| Glycerin SCHEMBL16008965 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL24864628 | 0.79 | ADRB2 (0.36) | KDM4EADRB2MEN1KMT2AADRB1 | |
| SCHEMBL17936208 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2ADRB2KMT2A | |
| SCHEMBL9110197 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22047323 | 0.76 | SCN1A (0.37) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214141-B | Benzodiazolium compounds as ENaC inhibitors | 企业治疗学有限公司 | 2022-05-31 | — | — | CN | disclosed |