Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336153 | 1.00 | GABRG2 (0.46) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL30336752 | 0.88 | GABRG2 (0.43) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL24865576 | 0.88 | GABRG2 (0.43) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL24865344 | 0.87 | CYP11B2 (0.44) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL24865138 | 0.87 | GABRG2 (0.48) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL31123368 | 0.87 | GABRG2 (0.48) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL31123189 | 0.87 | GABRG2 (0.44) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL24865342 | 0.87 | GABRG2 (0.44) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL24864968 | 0.84 | GABRG2 (0.44) | GABRG2GABRB3GABRA5SYKPDE3B | |
| SCHEMBL24865309 | 0.84 | TP53 (0.41) | GABRG2GABRB3GABRA5SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |