Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | BCL6 | P41182 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336308 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL24865481 | 0.75 | TRIM24 (0.61) | ALDH1A1MAPTGAASMN1; SMN2TP53 | |
| SCHEMBL18171839 | 0.75 | ALDH1A1 (0.64) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL30336558 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1MAPTGAASMN1; SMN2TP53 | |
| SCHEMBL24865228 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1MAPTGAASMN1; SMN2TP53 | |
| SCHEMBL24865397 | 0.73 | BCL6 (0.51) | ALDH1A1MAPTGAASMN1; SMN2TP53 | |
| SCHEMBL24865728 | 0.72 | KDM4E (0.54) | ALDH1A1MAPTGAASMN1; SMN2TP53 | |
| SCHEMBL30336374 | 0.72 | BRPF1 (0.48) | ALDH1A1MAPTSMN1; SMN2TP53BCL6 | |
| SCHEMBL24865113 | 0.72 | BRPF1 (0.48) | ALDH1A1MAPTSMN1; SMN2TP53BCL6 | |
| SCHEMBL24865065 | 0.72 | ALDH1A1 (0.67) | ALDH1A1GAARAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |