Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | BCL6 | P41182 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865206 | 0.82 | SMN1; SMN2 (0.53) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24865065 | 0.82 | ALDH1A1 (0.67) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30336923 | 0.82 | SMN1; SMN2 (0.53) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24865387 | 0.82 | SMN1; SMN2 (0.49) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30336657 | 0.82 | SMN1; SMN2 (0.49) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30336595 | 0.81 | SMN1; SMN2 (0.51) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24865365 | 0.81 | SMN1; SMN2 (0.57) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24865213 | 0.81 | SMN1; SMN2 (0.51) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20772684 | 0.80 | TRIM24 (0.51) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20777319 | 0.80 | SMN1; SMN2 (0.54) | TRIM24PKMLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327393-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-03 | — | — | US | disclosed |
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327393-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | TRIM24 4393/4885PKM 327/4885LMNA 1562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.