Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 10/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865487 | 0.83 | TTK (0.34) | TTKDCLK1LRRK2PDGFRBPDGFRA | |
| SCHEMBL24865568 | 0.80 | ROCK2 (0.47) | LRRK2EGFRULK1PDGFRBPDGFRA | |
| SCHEMBL30336110 | 0.80 | ROCK2 (0.47) | LRRK2EGFRULK1PDGFRBPDGFRA | |
| SCHEMBL24865446 | 0.80 | BCL6 (0.39) | DCLK1LRRK2 | |
| SCHEMBL31123302 | 0.80 | BCL6 (0.39) | DCLK1LRRK2 | |
| SCHEMBL30336615 | 0.80 | MAPT (0.39) | TTKLRRK2 | |
| SCHEMBL24865562 | 0.80 | MAPT (0.39) | TTKLRRK2 | |
| SCHEMBL24865626 | 0.78 | ADRA2A (0.47) | ULK1ULK2 | |
| SCHEMBL24864881 | 0.78 | HRH3 (0.39) | TTKDCLK1LRRK2PIK3CA | |
| SCHEMBL30336452 | 0.78 | HRH3 (0.39) | TTKDCLK1LRRK2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |