Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885112 | 1.00 | CNR2 (0.36) | CNR2HRH3BCL6JAK2SMN1; SMN2 | |
| SCHEMBL25194208 | 0.84 | CNR2 (0.37) | CNR2HRH3BCL6SMN1; SMN2PTK2 | |
| SCHEMBL25183899 | 0.83 | CNR2 (0.37) | CNR2BCL6PTK2KDM4EMAPT | |
| SCHEMBL25207364 | 0.82 | MAPT (0.37) | CNR2BCL6KDM4EMAPTNR4A1 | |
| SCHEMBL25188644 | 0.81 | KDM4E (0.39) | CNR2KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL25189837 | 0.81 | CNR2 (0.34) | CNR2BCL6JAK2PTK2ALDH1A1 | |
| SCHEMBL25191121 | 0.81 | NR1H2 (0.38) | CNR2BCL6JAK2SMN1; SMN2PTK2 | |
| SCHEMBL25215758 | 0.81 | ADRA2A (0.33) | HRH3SMN1; SMN2PTK2KDM4EMAPT | |
| SCHEMBL25188007 | 0.80 | L3MBTL1 (0.32) | SMN1; SMN2PTK2KDM4EMAPTALDH1A1 | |
| SCHEMBL30336093 | 0.80 | DRD2 (0.38) | CNR2JAK2SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |