Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 5/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865362 | 0.90 | MAPK10 (0.42) | MAPK10MAPK9FGFR1EGFRSCN10A | |
| SCHEMBL24865040 | 0.87 | MAPK10 (0.41) | MAPK10MAPK9FGFR1EGFRSCN10A | |
| SCHEMBL24865741 | 0.78 | CNR2 (0.34) | MAPK10MAPK9EGFRMAPK8 | |
| SCHEMBL24865300 | 0.77 | CNR2 (0.34) | — | |
| SCHEMBL24865675 | 0.76 | OPRK1 (0.36) | — | |
| SCHEMBL24865618 | 0.76 | CNR2 (0.36) | PTK2 | |
| SCHEMBL30885112 | 0.76 | CNR2 (0.36) | PTK2 | |
| SCHEMBL30336093 | 0.76 | DRD2 (0.38) | FGFR1 | |
| SCHEMBL24865620 | 0.76 | DRD2 (0.38) | FGFR1 | |
| SCHEMBL25042072 | 0.76 | HRH3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |