Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865740 | 0.92 | BCL6 (0.40) | GABRG2GABRB3GABRA5MEN1KMT2A | |
| SCHEMBL24865238 | 0.87 | GABRG2 (0.46) | GABRG2GABRB3GABRA5MEN1KMT2A | |
| SCHEMBL31123316 | 0.87 | GABRG2 (0.46) | GABRG2GABRB3GABRA5MEN1KMT2A | |
| SCHEMBL24865367 | 0.85 | GABRG2 (0.48) | GABRG2GABRB3GABRA5MEN1KMT2A | |
| SCHEMBL30885111 | 0.82 | BCL6 (0.46) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31123270 | 0.82 | BCL6 (0.50) | ALDH1A1SMN1; SMN2TP53LMNABCL6 | |
| SCHEMBL24865299 | 0.82 | BCL6 (0.50) | ALDH1A1SMN1; SMN2TP53LMNABCL6 | |
| SCHEMBL24865459 | 0.82 | BCL6 (0.46) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24865757 | 0.81 | KDM4E (0.43) | GABRG2GABRB3GABRA5MEN1KMT2A | |
| SCHEMBL31123282 | 0.81 | KDM4E (0.43) | GABRG2GABRB3GABRA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |