Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865639 | 0.92 | GABRG2 (0.43) | BCL6MEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL31123236 | 0.87 | SMN1; SMN2 (0.43) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL24865216 | 0.87 | SMN1; SMN2 (0.43) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL24865705 | 0.87 | CNR2 (0.39) | BCL6CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL31123296 | 0.85 | GABRG2 (0.39) | CNR2DDB1CRBNMEN1KMT2A | |
| SCHEMBL24865369 | 0.85 | GABRG2 (0.39) | CNR2DDB1CRBNMEN1KMT2A | |
| SCHEMBL31123312 | 0.85 | CNR2 (0.38) | BCL6CNR2MEN1KMT2AMAPT | |
| SCHEMBL29209022 | 0.85 | CNR2 (0.38) | BCL6CNR2MEN1KMT2AMAPT | |
| SCHEMBL24865368 | 0.85 | EGFR (0.45) | BCL6CNR2ALDH1A1 | |
| SCHEMBL24864837 | 0.85 | BCL6 (0.38) | BCL6CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |