Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123282 | 1.00 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL24865793 | 0.86 | ALDH1A1 (0.41) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL31123224 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1PKMLMNASMN1; SMN2TP53 | |
| SCHEMBL24865602 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1PKMLMNASMN1; SMN2TP53 | |
| SCHEMBL24865639 | 0.81 | GABRG2 (0.43) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL31123316 | 0.81 | GABRG2 (0.46) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL24865238 | 0.81 | GABRG2 (0.46) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL30336455 | 0.78 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL24865120 | 0.78 | KDM4E (0.47) | KDM4EMEN1KMT2AALDH1A1GABRG2 | |
| SCHEMBL24865689 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |