Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865648 | 0.91 | GRM4 (0.40) | ALDH1A1KDM4EMAPTBCL6NSD2 | |
| SCHEMBL24865699 | 0.86 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1HPGDKDM4E | |
| SCHEMBL24865606 | 0.82 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1HPGDKDM4E | |
| SCHEMBL24865759 | 0.81 | BCL6 (0.40) | ALDH1A1KDM4EMAPTBCL6MAPK1 | |
| SCHEMBL24865776 | 0.80 | CDC7 (0.43) | ALDH1A1BCL6BRD4 | |
| SCHEMBL30885115 | 0.79 | BCL6 (0.44) | HPGDKDM4EMAPTBCL6 | |
| SCHEMBL24865459 | 0.77 | BCL6 (0.46) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL24865755 | 0.77 | EGFR (0.40) | ALDH1A1KDM4EMAPTBCL6MAPK1 | |
| SCHEMBL24865299 | 0.77 | BCL6 (0.50) | ALDH1A1HSD17B10BCL6SMN1; SMN2HTT | |
| SCHEMBL24865669 | 0.77 | BCL6 (0.42) | ALDH1A1KDM4EMAPTBCL6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |