Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336647 | 1.00 | CNR2 (0.37) | CNR2CHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL24865653 | 0.91 | CNR2 (0.37) | CNR2CHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL24865093 | 0.81 | MAPT (0.36) | CNR2MAPTMAPK1TP53NR4A1 | |
| SCHEMBL24865763 | 0.79 | ULK1 (0.46) | CNR2MAPTMAPK1NR4A1TSHR | |
| SCHEMBL24864995 | 0.78 | ACHE (0.46) | CNR2MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL30336301 | 0.77 | SMN1; SMN2 (0.46) | CNR2CHRNA7MAPTMAPK1TP53 | |
| SCHEMBL24865099 | 0.77 | SMN1; SMN2 (0.46) | CNR2CHRNA7MAPTMAPK1TP53 | |
| SCHEMBL24865700 | 0.77 | ULK1 (0.37) | CNR2MAPTMAPK1TP53NR4A1 | |
| SCHEMBL30336302 | 0.77 | ULK1 (0.37) | CNR2MAPTMAPK1TP53NR4A1 | |
| SCHEMBL24865388 | 0.75 | EGFR (0.49) | CNR2CHRNA7MAPTMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |