Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336302 | 1.00 | ULK1 (0.37) | ULK1ULK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24865763 | 0.91 | ULK1 (0.46) | ULK1ULK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24865653 | 0.79 | CNR2 (0.37) | MAPTTSHRNR4A1CNR2KDM4E | |
| SCHEMBL24865672 | 0.77 | CNR2 (0.37) | MAPTTSHRNR4A1CNR2KDM4E | |
| SCHEMBL30336647 | 0.77 | CNR2 (0.37) | MAPTTSHRNR4A1CNR2KDM4E | |
| SCHEMBL30336970 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL24865606 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL30336301 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTTSHRNR4A1CNR2 | |
| SCHEMBL24865099 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTTSHRNR4A1CNR2 | |
| SCHEMBL24865093 | 0.75 | MAPT (0.36) | MAPTTSHRNR4A1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |