Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 7/20 | 0.41 |
| ▸ | JAK3 | P52333 | 7/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123276 | 1.00 | JAK1 (0.41) | JAK1JAK3CNR2JAK2CYP3A4 | |
| SCHEMBL24865172 | 0.87 | JAK1 (0.41) | JAK1JAK3JAK2CYP3A4P2RX3 | |
| SCHEMBL31123300 | 0.87 | JAK1 (0.41) | JAK1JAK3JAK2CYP3A4P2RX3 | |
| SCHEMBL24864995 | 0.79 | ACHE (0.46) | CNR2 | |
| SCHEMBL31123262 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL24865555 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL31123319 | 0.77 | BCL6 (0.40) | JAK1JAK3CNR2SYK | |
| SCHEMBL24865678 | 0.77 | BCL6 (0.40) | JAK1JAK3CNR2SYK | |
| SCHEMBL24865740 | 0.77 | BCL6 (0.40) | JAK1JAK3CNR2 | |
| SCHEMBL24865697 | 0.76 | MAPT (0.45) | JAK1JAK3JAK2CYP3A4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |