Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123253 | 0.91 | HTR1A (0.40) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL24865162 | 0.91 | HTR1A (0.40) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL31123284 | 0.91 | HTR1A (0.40) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL24865392 | 0.91 | HTR1A (0.40) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL24865168 | 0.90 | HTR1A (0.37) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL30336317 | 0.90 | HTR1A (0.37) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL24865554 | 0.90 | HTR1A (0.37) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL31123240 | 0.87 | HTR1A (0.42) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL24865205 | 0.87 | HTR1A (0.42) | HTR1AHTR2CGABRG2GABRB3GABRA5 | |
| SCHEMBL24864950 | 0.86 | GABRG2 (0.44) | HTR1AHTR2CGABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |