Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865437 | 0.89 | BCL6 (0.38) | KITKDM4EMAPTBCL6FGFR3 | |
| SCHEMBL24865645 | 0.80 | FGFR3 (0.34) | BCL6FGFR3KCNH2TRPV1 | |
| SCHEMBL24864955 | 0.80 | KDM4E (0.36) | KDM4EMAPTBCL6TRPA1EGFR | |
| SCHEMBL24865181 | 0.77 | KDM4E (0.35) | KITKDM4EMAPTBCL6SCN10A | |
| SCHEMBL24865215 | 0.75 | PTK2 (0.33) | KDM4EMAPTBCL6PTK2EGFR | |
| SCHEMBL24865751 | 0.74 | FGFR3 (0.39) | KDM4EMAPTFGFR3KCNH2EGFR | |
| SCHEMBL31123228 | 0.73 | BCL6 (0.49) | KDM4EMAPTBCL6SCN10A | |
| SCHEMBL24865177 | 0.73 | BCL6 (0.49) | KDM4EMAPTBCL6SCN10A | |
| SCHEMBL24865707 | 0.73 | JAK2 (0.32) | BCL6 | |
| SCHEMBL24865667 | 0.73 | ALK (0.33) | KDM4EMAPTBCL6ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |