Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102983 | 0.79 | P2RX4 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL12337290 | 0.79 | EPHX1 (0.54) | RECQLKDM4EMEN1KMT2AMAPT | |
| SCHEMBL27761713 | 0.79 | EPHX2 (0.54) | RECQLKDM4EMEN1KMT2AMAPT | |
| SCHEMBL13948465 | 0.79 | EPHX1 (0.48) | RECQLKDM4EMEN1KMT2AMAPT | |
| SCHEMBL27348781 | 0.78 | SMN1; SMN2 (0.58) | RECQLKDM4EMEN1KMT2AMAPT | |
| SCHEMBL13191363 | 0.78 | EPHX2 (0.53) | RECQLKDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4289843 | 0.78 | EPHX1 (0.53) | RECQLKDM4EMEN1KMT2AMAPT | |
| SCHEMBL13102958 | 0.77 | SIGMAR1 (0.70) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL19423928 | 0.76 | EPHX2 (0.59) | EPHX1EPHX2 | |
| SCHEMBL14530350 | 0.76 | L3MBTL1 (0.55) | RECQLKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |