Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22306149 | 0.90 | HTR4 (0.37) | USP2DRD2DRD4TP53SMN1; SMN2 | |
| SCHEMBL22952356 | 0.79 | HTR4 (0.38) | USP2DRD2DRD4TP53SMN1; SMN2 | |
| SCHEMBL22951190 | 0.79 | DRD2 (0.37) | USP2DRD2DRD4TP53SMN1; SMN2 | |
| SCHEMBL24865985 | 0.78 | EPHX1 (0.41) | DRD2DRD4KMT2AEPHX1EPHX2 | |
| SCHEMBL24865912 | 0.76 | HTR4 (0.33) | DRD2DRD4HTR4SIGMAR1DPP4 | |
| SCHEMBL24865914 | 0.75 | EPHX1 (0.36) | USP2DRD2TP53SMN1; SMN2EPHX1 | |
| SCHEMBL25089654 | 0.75 | EPHX1 (0.46) | USP2DRD2DRD4TP53SMN1; SMN2 | |
| SCHEMBL14520631 | 0.74 | USP2 (0.59) | USP2DRD2DRD4TP53SMN1; SMN2 | |
| SCHEMBL22302357 | 0.74 | HTR4 (0.43) | DRD2DRD4TP53SMN1; SMN2EPHX1 | |
| SCHEMBL9891801 | 0.73 | MAPT (0.44) | KMT2AEPHX1EPHX2ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |