Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22306015 | 0.90 | EPHX1 (0.48) | EPHX1EPHX2HTR4HTR3ACACNA1I | |
| SCHEMBL9891801 | 0.89 | MAPT (0.44) | EPHX1EPHX2DPP4PREPFAP | |
| SCHEMBL26330243 | 0.88 | HTR4 (0.41) | EPHX1EPHX2HTR4HTR3ACACNA1I | |
| SCHEMBL25089654 | 0.84 | EPHX1 (0.46) | EPHX1EPHX2HTR4CACNA1IKCNH2 | |
| SCHEMBL22302357 | 0.83 | HTR4 (0.43) | EPHX1EPHX2HTR4CACNA1IKCNH2 | |
| SCHEMBL22169792 | 0.83 | EPHX1 (0.52) | EPHX1EPHX2CACNA1IKCNH2DPP4 | |
| SCHEMBL12413662 | 0.81 | DRD2 (0.43) | EPHX1EPHX2DPP4PREPFAP | |
| SCHEMBL24866005 | 0.78 | USP2 (0.39) | EPHX1EPHX2HTR4DPP4PREP | |
| SCHEMBL25089683 | 0.78 | HTR4 (0.41) | EPHX1EPHX2HTR4CACNA1IKCNH2 | |
| SCHEMBL1107035 | 0.78 | TDP1 (0.52) | EPHX1EPHX2DPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283263-A1 | CITRATE SALT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | FOGHORN THERAPEUTICS INC. (US) | 2023-01-12 | — | — | WO | disclosed |