SCHEMBL2486679

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3518969	0.92	CYP2D6 (0.37)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL16797552	0.89	CA12 (0.38)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL18372671	0.86	CYP2D6 (0.37)	CYP2D6CYP1A2KMT2ASMN1; SMN2STAT3
	SCHEMBL244134	0.81	CYP2D6 (0.43)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL962353	0.81	CYP2D6 (0.39)	CYP2D6CYP1A2KMT2ASMN1; SMN2STAT3
	SCHEMBL15348113	0.79	CA12 (0.39)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL336340	0.79	ALDH1A1 (0.44)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL334939	0.79	ACHE (0.44)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL16104743	0.78	KMT2A (0.37)	CYP2D6CYP1A2CA12CA1CA9
	SCHEMBL967917	0.78	ALDH1A1 (0.43)	CA12CA1CA9ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.